Boston, MA SEPTEMBER 19, 2023 – Sean Doherty has been honored as a PharmaVoice 100 winner. This annual list recognizes the most inspiring people in the life sciences industry.
PharmaVoice100 honorees are selected from a pool of nominations submitted by readers and colleagues, and then evaluated by the PharmaVoice team. This year’s honorees include: Standout execs, Trailblazers, Cancer care visionaries, Clinical trial gurus, Patient heroes, Entrepreneurs, Tech wizards, Rare disease warriors, and Brand and commercialization pros.
“This industry is a ground-breaking one capable of changing the world through science and technology. These honorees inspire advancements by guiding their teams, supporting their patients, and propelling their organizations’ missions forward. We are excited to recognize their contributions through this annual list,” said Meagan Parrish, lead editor of PharmaVoice.
Since 2005, the PharmaVoice 100 — and Red Jacket honorees — have become one of the publication’s most anticipated features. PharmaVoice developed the only awards program in the industry to recognize individuals of all ages and sectors of the life sciences — from academia to nonprofits, Big Pharma, startups, tech companies, service providers and more. The PharmaVoice 100 contains a diverse mix of professionals across a range of disciplines — from the clinic to the C-suite — who are making meaningful contributions in their fields and striving to improve outcomes for patients.
This year, we will also celebrate our 2023 PharmaVoice 100 honorees during a virtual two-day event PharmaVoice is hosting with its sister publication BioPharmaDive called “The Next Frontier of the Life Sciences” on Oct. 25-26. Hosted by award-winning journalists, this event will feature a range of keynotes, panel discussions and fireside chats on the critical trends facing the industry including innovation, genetic medicine, research hot spots, the biotech market, clinical trial tech advancements and more.
The event will wrap up on Thursday Oct. 26 at 3:40p with a PharmaVoice 100 celebration where we will salute this year’s honorees and announce the 2023 Red Jacket (the PharmaVoice 100 “hall of fame”) recipients.
—
About the JDRF T1D Fund
Our aim is to create a new investment market aimed at delivering solutions to those living with or at risk of developing T1D. Launched in December 2016, the T1D Fund is a combination of venture capital and philanthropy focused solely on T1D. It’s the first scale, mission-driven venture philanthropy fund focused on equity investments in companies developing life-changing T1D products. The portfolio consists of therapeutics, devices, vaccines, and diagnostics. We already have made several investments and the list will only continue to grow.
About PharmaVoice
PharmaVoice is a leading industry publication operated by Industry Dive. Our stories deliver the most important voices and ideas in the life sciences to industry leaders.
About Industry Dive
Industry Dive, an Informa business, is a leading business journalism company. Over 14 million decision-makers across 20+ competitive industries rely on our exclusive insight and analysis delivered through more than 30 publications.
Enthera Pharmaceuticals (“Enthera”), a biotech company developing first-in-class biologics for selected autoimmune conditions, today announces the start of a Phase 1 first-in-human (FIH) clinical trial with its lead candidate Ent001. Ent001 is a monoclonal antibody (mAb) targeting the IGFBP3/TMEM219 pathway, which plays a critical role in both inflammatory bowel disease (IBD) and type 1 diabetes (T1D). Elevated levels of IGFBP3 bind to the TMEM219 receptor, causing apoptosis of both colonic stem cells in the gut and insulin-producing beta cells in the pancreas. Ent001 is designed to bind to TMEM219 and prevent cell death and the inflammation underlying these disease states. The trial in healthy volunteers will evaluate Ent001’s safety and tolerability and establish optimal dose levels for subsequent trials in patients with IBD and T1D, the target indications for the next stage of Ent001’s clinical development.
“The initiation of this trial is a major development milestone for Ent001 and transitions Enthera into a clinical stage company. The data we gather from this study will be instrumental to optimize the development of our lead candidate and enable future development in IBD and T1D,” said Aled Paton Williams, CEO of Enthera.
The Phase 1 trial will evaluate Ent001 in up to 30 healthy adult volunteers in a randomised, double-blind, placebo-controlled single ascending dose (SAD) study in the Netherlands. In addition to safety, the trial will assess Ent001’s pharmacokinetics, pharmacodynamics, and immunogenicity.
“This trial builds on our robust preclinical data that revealed a strong safety profile and demonstrated noteworthy results with Ent001’s unique mode of action in well-established animal disease models. We look forward to applying our unique understanding of the recently discovered IGFBP3/TMEM219 axis to establish Ent001’s potential as a first-in-class therapeutic with the ability to halt and reverse disease progression in IBD and T1D,” said Filippo Canducci, Chief Medical Officer of Enthera.
About Enthera Pharmaceuticals
Enthera Srl is a biotech company developing first-in-class biologics to transform the treatment paradigm for specific autoimmune conditions by preserving and re-establishing cell and organ function. The Company’s primary target indications are inflammatory bowel disease (IBD) and type 1 diabetes (T1D). Enthera’s pioneering approach capitalizes on the key discovery of the IGFBP3/TMEM219 pathway, which is involved in stem cell and beta cell apoptosis in the gut and pancreas, respectively.
Enthera is a private company headquartered in Milan, Italy, and founded in 2016 by Prof. Paolo Fiorina and Dr. Francesca D’Addio at BiovelocITA, Italy’s first biotech accelerator. The Company is backed by Sofinnova Partners, AbbVie INC, JDRF T1D Fund, Roche Finance LTD and a number of private investors. Enthera’s discovery engine and assets are protected by a broad portfolio of patents.
For further information: www.entherapharmaceuticals.com
Enthera Pharmaceuticals
Aled Williams, CEO
info@entherapharmaceuticals.com
Trophic Communications
Valeria Fisher or Veronika Máté
+49 175 8041816 or +49 160 90816161
enthera@trophic.eu